Integrative Structural Modeling
Combining EM, crosslinking, SAXS, and other data into multi-scale macromolecular models.
Integrative Structural Modeling addresses combining em, crosslinking, saxs, and other data into multi-scale macromolecular models. As a subfield of structural biology, it sits within the broader biology branch of the Charted science tree and connects upward to the methodological themes of its parent area.
A more detailed frontier sourcing pass for this topic is deferred to a follow-up OpenAlex wave; the current sources include Highly accurate protein structure prediction with AlphaFold (Jumper et al., 2021), each kept as a placeholder anchor for the next iteration. See the parent topic (biology/structural-biology) for the wider context this page will eventually slot into.
Prerequisites
Sources
- paper · primary · 2021jumper-2021, evans-richard-2021, hassabis-2021
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